Calgary, Alberta
April 26, 2006
SemBioSys Genetics Inc.
(TSX:SBS), a biotechnology company developing a broad pipeline
of protein pharmaceuticals and non-pharmaceutical products,
today announced the completion of key milestones in its GLA rich
safflower oil project with
Arcadia Biosciences, Inc. The delivery of safflower seeds
from plant lines containing gamma linolenic acid (GLA),
transformed utilizing Arcadia's proprietary genes, fulfills
SemBioSys' primary responsibilities under the funded agreement
between SemBioSys and Arcadia. GLA is an essential fatty acid
with potential for use in topical, medical food and
nutraceutical markets.
"Completing the key milestones
on this project demonstrates the ability of our safflower
transformation technology to deliver nutraceutical rich oil
products. We believe the level of GLA expression achieved in
safflower confirms that our oil engineering technology is an
enabling tool for the broad commercial production and use of
GLA," said Andrew Baum, President and CEO of SemBioSys Genetics
Inc. "The successful completion of the GLA project further
validates the ability of our team to deliver on milestone
commitments to existing partners like Arcadia, and to other
potential partners in the future."
SemBioSys produced safflower
plants that accumulated in excess of 65% total GLA seed oil,
exceeding the milestone targets for GLA accumulation. As part of
the partnership agreement, SemBioSys will receive license
payments upon Arcadia's achievement of scale-up milestones, The
Company will also receive ongoing sales royalties from Arcadia
for GLA rich safflower oil upon successful product
commercialization.
GLA is an omega-6
polyunsaturated fatty acid, which along with omega-3 fatty
acids, is the recommended source of dietary fats in the Dietary
Guidelines for Americans 2005. GLA is a natural
anti-inflammatory with benefits for cardiac, joint, skin, and
neurological health. Areas where GLA may be beneficial include
infant nutrition, atopic eczema, dermatitis, diabetic
neuropathy, breast pain, premenstrual syndrome symptoms,
rheumatoid arthritis, high blood pressure, skin health and
general inflammation. Current GLA supply is expensive and
unreliable, greatly limiting its use as a dietary supplement.
Safflower-produced GLA offers a low-cost, reliable and scalable
source of omega-6 fatty acid.
Calgary, Alberta-based SemBioSys Genetics Inc. is a
biotechnology company focused on the development,
commercialization and production of protein-based
pharmaceuticals and non-pharmaceutical products based on its
plant genetic engineering skills and proprietary oilbody-oleosin
technology platform - the Stratosome(TM) Biologics System. Its
two lead pharmaceutical product candidates are insulin and a
developmental cardiovascular drug called Apo AI. It also has a
series of non-pharmaceutical products addressing animal and
aquaculture health, nutritional oils and human topical markets.
SemBioSys currently has funded partnership agreements with
Martek Biosciences Corporation, Lonza Inc. and Arcadia
Biosciences, Inc. |